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Isopropyl alcohol

Isopropyl alcohol


Chemical & Physical Properties:

  • Product Name: Isopropyl alcohol
  • Other Name: IPA
  • CAS No.:67-63-0
  • UN No.:1219
  • EINECS No.: 200-661-7
  • Purity:99.9%min
  • Molecular Weight: 60.10
  • Class:3
  • Chemical Formula: C3H8O
  • Appearance: transparent clear liquid
  • Melting point:-89.5 °C
  • Boiling point:82 °C(lit.)
  • Density:0.785 g/mL at 25 °C(lit.)
  • vapor density:2.1 (vs air)
  • vapor pressure:33 mm Hg ( 20 °C)
  • refractive index:n20/D 1.377(lit.)
  • Flash point:53 °F
  • storage temp.:Store at +5°C to +30°C.
  • solubility-water: soluble (completely)
  • pka:17.1(at 25℃)
  • form: Low Melting Solid



Isopropanol is also known as isopropyl alcohol. It is the simplest secondary alcohol and is one of the isomers of n-propanol. It is a kind of flammable liquid which is colorless with a strong smell similar to the smell of a mixture of ethanol and acetone. It is soluble in water, alcohol, ether, benzene, chloroform, and most organic solvents and is miscible with water, alcohol, and ether and can form azeotrope with water. Density (specific gravity): 0.7863g/cm3, melting point:-88.5 ℃, boiling point: 82.5 ℃, flash point: 11.7 ℃, ignition point: 460 ℃, refractive index: 1.3772. Its vapor can cause slight irritation on the eyes, nose, and throat; it can be absorbed through the skin. Its vapor can form an explosive mixture with air. Its explosion limit is 2.0% to 12% (by volume). It belongs to a moderate explosive hazardous material and flammable, low-toxic substance. The toxicity of its vapors is twice as high as ethanol while oral administration causes the opposite toxicity.


  1. As a chemical raw material, isopropanol can produce acetone, hydrogen peroxide, methyl isobutyl ketone, diisobutyl ketone, isopropylamine, isopropyl ether, isopropyl chloride, as well as fatty acid isopropyl ester and chlorine Substitute fatty acid isopropyl ester and so on. Fine chemicals, can be used to produce isopropyl nitrate, isopropyl xanthate, triisopropyl phosphite, aluminum isopropoxide, medicine, pesticides, etc. It can also be used to produce diisopropyl acetone, isopropyl acetate, and Thymol and gasoline additives.
  2. As a solvent, it can be freely mixed with water, and its solubility for lipophilic substances is stronger than ethanol. It can be used as a solvent for nitrocellulose, rubber, paint, shellac, alkaloids, etc. It can be used to produce coatings, inks, extractants, aerosols, etc. It can also be used as an antifreeze, cleaning agent, additive for blending gasoline, dispersant for pigment production, fixing agent for printing and dyeing industry, antifogging agent for glass and transparent plastic, etc.
  3. As a chromatographic standard for the determination of barium, calcium, copper, magnesium, nickel, potassium, sodium, strontium, nitrous acid, cobalt, etc.
  4. In the electronics industry, it can be used as a cleaning degreaser. In the oil industry, the extractant of cottonseed oil can also be used for degreasing of animal-derived tissue membranes.

Chemical Properties:

Isopropyl alcohol is a clear, colorless, mobile, volatile, flammable liquid with a characteristic, spirituous odor resembling that of a mixture of ethanol and acetone; it has a slightly bitter taste. It is miscible with water, ethyl ether, and ethyl alcohol. Isopropyl alcohol is incompatible with strong oxidizers, acetaldehyde, chlorine, ethylene oxide, acids, and isocyanates.


Items Standard testing Result
appearance transparent clear liquid coincidence
purity% 99.9 99.92
APHA 10 max 5
water content% 0.05max 0.04
acidity(as acetic acid)% 0.002 0.0008
density at 20ºC(g/cm3) 0.784-0.786 0.7851
evaporation resuide% 0.002max 0.0008
carbonyl value% 0.02 0.0028
sulfide content(mg/kg) 2 0.3


800kg*20IBC drum
800kg*32 IBC drum

Health Hazard

Exposures to isopropyl alcohol cause irritation to the eyes and mucous membranes. Exposures to isopropyl alcohol for 3–5 min (400 ppm) caused mild irritation of the eyes, nose, and throat, and at 800 ppm these symptoms became severe. Ingestion or an oral dose of 25 mL in 100 mL of water produced hypotension, facial flushing, bradycardia, and dizziness. Ingestion in large quantities caused extensive hemorrhagic tracheobronchitis, bronchopneumonia, and hemorrhagic pulmonary edema. Prolonged skin contact with isopropyl alcohol caused eczema and sensitivity. Delayed dermal absorption is attributed to a number of pediatric poisonings that have occurred following repeated or prolonged sponge bathing with isopropyl alcohol to reduce fever. In several cases, symptoms included respiratory distress, stupor, and coma. Laboratory animals exposed to isopropyl alcohol develop poisoning with symptoms of hind leg paralysis, unsteadiness, lack of muscular coordination, respiratory depression, and stupor. Isopropyl alcohol is a potent CNS depressant, and in large doses causes cardiovascular depression.

Fire Hazard

Isopropyl Alcohol(IPA) is highly flammable in its liquid and vapor forms and flammable atmospheres can be created at temperatures as low as 540°F /120℃. This means that any environment where IPA is being used needs to be well-ventilated. It should be kept away from heat and open flame. As the vapor is heavier than air, it may spread along the ground, so care needs to be taken that the vapor is not ignited by a distant source.

Pharmaceutical Applications

Isopropyl alcohol (propane-2-ol) is used in cosmetics and pharmaceutical formulations, primarily as a solvent in topical formulations. ( It is not recommended for oral use owing to its toxicity.

Although it is used in lotions, the marked degreasing properties of isopropyl alcohol may limit its usefulness in preparations used repeatedly. Isopropyl alcohol is also used as a solvent both for tablet film-coating and for tablet granulation, where the isopropyl alcohol is subsequently removed by evaporation. It has also been shown to significantly increase the skin permeability of nimesulide from carbomer 934.

Isopropyl alcohol has some antimicrobial activity and a 70% v/v aqueous solution is used as a topical disinfectant. Therapeutically, isopropyl alcohol has been investigated for the treatment of postoperative nausea or vomiting.

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